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bioRxiv
|
2025
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In vitro 2 In vivo : Bidirectional and High-Precision Generation of In Vitro and In Vivo Neuronal Spike Data

Masanori Shimono
Preprint
Brain Slices
MaxOne
bioRxiv
|
2025
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MAIS: an in-vitro sandbox enables adaptive neuromodulation via scalable neural interfaces

Haoman Chen, Fanxuan Chen, Xinyu Chen, Yang Liu, Junpeng Xu, Jiajun Li, Xueying Bao, Yuzhe Chen, Haojun Sun, Jiaju Jiang, Fangzhou Ye, Jianzhong Su, Yang Gen, Fangfu Ye, Zhouguang Wang, Liyu Liu, Saiyin Hexige, Xiaokun Li, Lixiang Ma, Jianwei Shuai
Preprint
Neurocomputing
Neuronal Cell Cultures
MaxOne
bioRxiv
|
2025
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APP overexpression delays synaptic development and alters neuronal network properties

Fulin Ma, Himanshu Akolkar, Ryad Benosman, Karl Herrup
Preprint
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2025
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Induction and long-term maintenance of hindbrain-like neural stem cells in xeno- and basic fibroblast growth factor-free conditions

Ziadoon Al-Akashi, Denise Zujur, Nicholas Boyd-Gibbins, Nathalie Eileen Wiguna, Masato Nakagawa, Tetsuhiro Kikuchi, Asuka Morizane, Jun Takahashi, Makoto Ikeya
Preprint
Functional Phenotyping
Organoids
MaxLab Live
MaxOne
bioRxiv
|
2025
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Modeling Organoid Population Electrophysiology Dynamics

Matthew J. Roos, Diego Luna, Dowlette-Mary Alam El Din, Thomas Hartung, Lena Smirnova, Alex Proescher, Erik C. Johnson
Preprint
Neurocomputing
Organoids
MaxTwo
bioRxiv
|
2025
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Chronic social defeat causes dysregulation of systemic glucose metabolism via the cerebellar fastigial nucleus

Taiga Ishimoto, Takashi Abe, Yuko Nakamura, Tomonori Tsuyama, Kunio Kondoh, Naoto Kajitani, Kaede Yoshida, Yuichi Takeuchi, Kan X. Kato, Shucheng Xu, Maru Koduki, Momoka Ichimura, Takito Itoi, Kenta Shimba, Yoshifumi Yamaguchi, Masabumi Minami, Shinsuke Koike, Kiyoto Kasai, Jessica J. Ye, Minoru Takebayashi, Kazuya Yamagata, Chitoku Toda
Preprint
Disease Modeling
Pharmacology & Toxicology
Brain Slices
MaxOne
Neuro-Oncology
|
2025
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Targeting PGE2 mediated senescent neuron improves tumour therapy

Jianyi Zhao, Linshi Wu, Gang Cai, Dan Ou, Keman Liao, Jian Yang, Li Zhou, Renhua Huang, Shukai Lin, Xi Huang, Qi Lv, Juxiang Chen, Lu Cao, Jiayi Chen, Yingying Lin
Journal Article
Disease Modeling
Functional Phenotyping
Neuronal Cell Cultures
MaxLab Live
MaxOne
Advanced Functional Materials
|
2025
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An Implantable Biohybrid Neural Interface Toward Synaptic Deep Brain Stimulation

Léo Sifringer, Alex Fratzl, Blandine F. Clément, Parth Chansoria, Leah S. Mönkemöller, Jens Duru, Stephan J. Ihle, Simon Steffens, Anna Beltraminelli, Eylul Ceylan, Julian Hengsteler, Benedikt Maurer, Sean M. Weaver, Christina M. Tringides, Katarina Vulić, Srinivas Madduri, Marcy Zenobi-Wong, Botond Roska, János Vörös, Tobias Ruff
Journal Article
Microphysiological Systems
Retina
Organoids
MaxOne
bioRxiv
|
2025
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Self-organization of high-dimensional geometry of neural activity in culture

Asahi Nakamuta, Dai Akita, He Zhang, Yuta Kawahara, Hirokazu Takahashi, Jun-nosuke Teramae
Preprint
Neuronal Cell Cultures
MaxOne
bioRxiv
|
2025
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Repetitive stimulation modifies network characteristics of neural organoid circuits

Siu Yu A. Chow, Huaruo Hu, Tomoya Duenki, Takuya Asakura, Sota Sugimura, Yoshiho Ikeuchi
Preprint
Organoids
MaxLab Live
MaxOne
bioRxiv
|
2025
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Engineered biological neural networks as basic logic operators

Joël Küchler, Katarina Vulić, Haotian Yao, Christian Valmaggia, Stephan Johannes Ihle, Sean Weaver, Janos Vörös
Preprint
Microphysiological Systems
Neuronal Cell Cultures
MaxOne
Stem Cell Reports
|
2025
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Swift induction of human spinal lower motor neurons and robust ALS cell screening via single-cell imaging

Selena Setsu, Satoru Morimoto, Shiho Nakamura, Fumiko Ozawa, Kagistia Hana Utami, Ayumi Nishiyama, Naoki Suzuki, Masashi Aoki, Yukio Takeshita, Yukihide Tomari, Hideyuki Okano
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
Journal of Neurochemistry
|
2025
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Regulation of Dendrite and Dendritic Spine Formation by TCF20

Ersilia Vinci, Stefania Beretta, Veronica Colombo, Antonio Zippo, Alberto Catanese, Christoph Wiegreffe, Stefan Britsch, Tobias Boeckers, Chiara Verpelli, Carlo Sala
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxTwo
bioRxiv
|
2025
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An in vitro platform for characterizing axonal electrophysiology of individual human iPSC-derived nociceptors

Blandine F. Clément, Lorenzo Petrella, Lea Wallimann, Jens Duru, Christina M. Tringides, János Vörös, Tobias Ruff
Preprint
Functional Phenotyping
Method Development
Microphysiological Systems
Pharmacology & Toxicology
Organoids
MaxOne
bioRxiv
|
2025
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Recreating coronary vascularization and sympathetic innervation of myocardium on a human pluripotent stem cell-derived heart organoid

Mariana A. Branco, Mafalda Marques Nunes, Ana Luísa Rayagra, Miguel F. Tenreiro, Joaquim M.S. Cabral, Maria Margarida Diogo
Preprint
Functional Phenotyping
Organoids
MaxTwo
Advanced Healthcare Materials
|
2025
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Insulative Compression of Neuronal Tissues on Microelectrode Arrays by Perfluorodecalin Enhances Electrophysiological Measurements

Tomoya Duenki, Yoshiho Ikeuchi
Journal Article
Microphysiological Systems
Retina
Neuronal Cell Cultures
Organoids
MaxOne
PLOS ONE
|
2024
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Theoretical analysis of neuronal network’s response under different stimulus

Haosen Xue, Zeying Lu, Yueheng Lan, Lili Gui, Xiaojuan Sun
Journal Article
Functional Phenotyping
Neuronal Cell Cultures
MaxOne
arXiv
|
2024
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Starting a Synthetic Biological Intelligence Lab from Scratch

Md Sayed Tanveer, Dhruvik Patel, Hunter E. Schweiger, Kwaku Dad Abu-Bonsrah, Brad Watmuff, Azin Azadi, Sergey Pryshchep, Karthikeyan Narayanan, Christopher Puleo, Kannathal Natarajan, Mohammed A. Mostajo-Radji, Brett J. Kagan, Ge Wang
Preprint
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2024
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Multiscale Cloud-Based Pipeline for Neuronal Electrophysiology Analysis and Visualization

Jinghui Geng, Kateryna Voitiuk, David F. Parks, Ash Robbins, Alex Spaeth, Jessica L. Sevetson, Sebastian Hernandez, Hunter E. Schweiger, John P. Andrews, Spencer T. Seiler, Matthew A. T. Elliott, Edward F. Chang, Tomasz J. Nowakowski, Rob Currie, Mohammed A. Mostajo-Radji, David Haussler, Tal Sharf, Sofie R. Salama, Mircea Teodorescu
Preprint
Disease Modeling
Neuronal Cell Cultures
Organoids
Brain Slices
MaxOne
bioRxiv
|
2024
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Goal-Directed Learning in Cortical Organoids

Ash Robbins, Hunter E. Schweiger, Sebastian Hernandez, Alex Spaeth, Kateryna Voitiuk, David F. Parks, Tjitse van der Molen, Jinghui Geng, Tal Sharf, Mohammed A. Mostajo-Radji, David Haussler, Mircea Teodorescu
Preprint
Neurocomputing
Organoids
MaxLab Live
MaxOne
PLOS ONE
|
2024
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RT-Sort: An action potential propagation-based algorithm for real time spike detection and sorting with millisecond latencies

Tjitse van der Molen, Max Lim, Julian Bartram, Zhuowei Cheng, Ash Robbins, David F. Parks, Linda R. Petzold, Andreas Hierlemann, David Haussler, Paul K. Hansma, Kenneth R. Tovar, Kenneth S. Kosik
Journal Article
Neuronal Cell Cultures
MaxOne
HardwareX
|
2024
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A modular and flexible open source cell incubator system for mobile and stationary use

Jens Duru, Benedikt Maurer, Tobias Ruff, Katarina Vulić, Julian Hengsteler, Sophie Girardin, János Vörös, Stephan J. Ihle
Journal Article
Method Development
Retina
MaxOne
Advanced Science
|
2024
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Direct-Print 3D Electrodes for Large-Scale, High-Density, and Customizable Neural Interfaces

Pingyu Wang, Eric G. Wu, Hasan Ulusan, Eric Tianjiao Zhao, A.J. Phillips, Alexandra Kling, Madeline Rose Hays, Praful Krishna Vasireddy, Sasidhar Madugula, Ramandeep Vilkhu, Andreas Hierlemann, Guosong Hong, E. J. Chichilnisky, Nicholas A. Melosh
Journal Article
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Nano Letters
|
2024
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Solid-State Nanopores for Spatially Resolved Chemical Neuromodulation

F. Vacca, F. Galluzzi, M. Blanco-Formoso, T. Gianiorio, A.F. De Fazio, F. Tantussi, S. Stürmer, W. Haq, E. Zrenner, A. Chaffiol, C. Joffrois, S. Picaud, F. Benfenati, F. De Angelis, E. Colombo
Journal Article
Retina
MaxOne
Nature Neuroscience
|
2024
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Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices

John P. Andrews, Jinghui Geng, Kateryna Voitiuk, Matthew A. T. Elliott, David Shin, Ash Robbins, Alex Spaeth, Albert Wang, Lin Li, Daniel Solis, Matthew G. Keefe, Jessica L. Sevetson, Julio A. Rivera De Jesús, Kevin C. Donohue, H. Hanh Larson, Drew Ehrlich, Kurtis I. Auguste, Sofie Salama, Vikaas Sohal, Tal Sharf, David Haussler, Cathryn R. Cadwell, David V. Schaffer, Edward F. Chang, Mircea Teodorescu, Tomasz Jan Nowakowski
Journal Article
Disease Modeling
Functional Phenotyping
Pharmacology & Toxicology
Brain Slices
MaxLab Live
MaxOne
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