Results:1
Acute recordings of spinal cord organoids generated via a commercially available kit from ACROBiosystems, performed on MaxTwo 6-Well Plate with Liquid Holder.
This webinar presents how combining transcription factor overexpression with developmental signaling modulation enables the generation of diverse human neuron types. It highlights large-scale single-cell transcriptomics and functional profiling approaches used to link neuronal identity with activity, connectivity, and maturation.
Learn how combining MaxTwo Multi-Well High-Density MEA technology with FUJIFILM hiPSC-derived neurons enables advanced investigation of neurodegenerative disease mechanisms, including comparative analyses of Parkinson’s, ALS, and FTD models versus healthy controls. The talk also highlights how optimized HD-MEA assays detect subtle functional phenotypes to precisely characterize disease models.
This guide explains how to process MaxLab Live recordings to extract single-neuron activity using SpikeInterface for spike sorting and DeePhys for downstream functional analysis.
Learn how micro- and nano-channel PDMS platforms enable directional neuronal network fabrication at single-neuron resolution and support personalized disease modeling using patient-derived cells. The talk also demonstrates how biophysical modeling and information-theoretic analysis of neuronal networks on a chip reveal synaptic receptor alterations and altered information flow in glioblastoma-infiltrated networks.
Learn how inter-regional connectivity underlies complex brain functions and how neural organoid networks can model these circuits in vitro. The talk highlights how HD-MEAs enable detailed analysis of organoid network activity and functional connectivity.
Developing next-generation in-vitro phenotypic assays for Huntington's disease by combining precision reprogrammed hiPSC-derived disease models with high-density microelectrode arrays.