Driving innovation in human neural models of development and disease
May 26, 2026 | 17:00 CEST
8:00 PDT | 11:00 EDT | 16:00 BST
Webinar Hightlights
A webinar with Nature featuring MaxWell Biosystems' users presenting breakthrough research in neurodevelopment and neurological disease. In this webinar you will learn:
- How human neural models can better support research in development and disease.
- New approaches linking molecular changes to neuronal function and axonal vulnerability.
- Strategies to generate more diverse and biologically relevant neural cell types in vitro.
- Advances in neuron engineering and molecular analysis for more informative in vitro systems.
Registration in now open: register here!
The webinar covered
- Breakthrough research from MaxWell Biosystems users in neurodevelopment and neurological disease.
- Advances in neuron engineering and molecular analysis.
- How human neural models support development and disease research.
- Approaches linking molecular changes to neuronal function and axonal vulnerability.
- Strategies for generating more diverse and biologically relevant neural cell types in vitro.
Agenda
From neuronal subtype programming to axonal vulnerability in human neural models
Abstract
Human neuronal models are increasingly used to investigate nervous system development, disease mechanisms and therapeutic strategies. Yet key challenges remain: generating the right neuronal subtypes in vitro, capturing functionally relevant phenotypes, and linking molecular changes to neuronal physiology and behaviour. Within this evolving landscape, human in vitro systems provide an important foundation for complementary humanized models, which help extend findings until more complex human model platforms are established.
In this webcast, the speakers will share recent work that addresses these gaps using complementary approaches. The session will feature spatial transcriptomics to resolve subcellular RNA localization in neurons, offering new insight into axonal vulnerability and local translation programs implicated in neurodegenerative disease, such as ALS. It will also highlight systematic patterning strategies that broaden the diversity of human neurons produced in vitro, supporting subtype-specific models with improved biological relevance.
Together, these presentations provide an overview of advances in neuron engineering and molecular analysis that are enabling more informative in vitro systems for studying brain development and neurological disease.
Learn:
- How human neural models can better support research in development and disease
- What new approaches are helping connect molecular changes to neuronal function and axonal vulnerability
- How researchers can generate more diverse and biologically relevant neural cell types in vitro
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