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Advanced Materials
|
2023
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A Neurospheroid-Based Microrobot for Targeted Neural Connections in a Hippocampal Slice

Eunhee Kim, Sungwoong Jeon, Yoon-Sil Yang, Chaewon Jin, Jin-young Kim, Yong-Seok Oh, Jong-Cheol Rah, Hongsoo Choi
Journal Article
Microphysiological Systems
Organoids
Brain Slices
MaxLab Live
MaxOne
Frontiers in Neuroinformatics
|
2023
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Predicting in vitro single-neuron firing rates upon pharmacological perturbation using Graph Neural Networks

Taehoon Kim, Dexiong Chen, Philipp Hornauer, Vishalini Emmenegger, Julian Bartram, Silvia Ronchi, Andreas Hierlemann, Manuel Schröter, Damian Roqueiro
Journal Article
Neurocomputing
Pharmacology & Toxicology
Neuronal Cell Cultures
MaxTwo
Frontiers in Neuroscience
|
2023
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Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks

Yuya Sato, Hideaki Yamamoto, Hideyuki Kato, Takashi Tanii, Shigeo Sato, Ayumi Hirano-Iwata
Journal Article
Microphysiological Systems
Neuronal Cell Cultures
MaxLab Live
MaxOne
Biomaterials Research
|
2022
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A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement

Xiaobo Han, Naoki Matsuda, Yuto Ishibashi, Aoi Odawara, Sayuri Takahashi, Norie Tooi, Koshi Kinoshita, Ikuro Suzuki
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxOne
Brain
|
2022
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Downregulation of PMP22 ameliorates myelin defects in iPSC-derived human organoid cultures of CMT1A

Jonas Van Lent, Leen Vendredy, Elias Adriaenssens, Tatiana Da Silva Authier, Bob Asselbergh, Marcus Kaji, Sarah Weckhuysen, Ludo Van Den Bosch, Jonathan Baets, Vincent Timmerman
Journal Article
Disease Modeling
Organoids
MaxLab Live
MaxTwo
SSRN
|
2022
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Generation of Human Striatal-Midbrain Assembloids From Human Pluripotent Stem Cells to Model Alpha-Synuclein Propagation

Hoang-Dai Tran, Min-Kyoung Shin, Charlotte Denman, Run-Run Han, Bernd Kuhn, Gordon Arbuthnott, Junghyun Jo
Preprint
Disease Modeling
Organoids
MaxLab Live
MaxOne
NeurIPS
|
2022
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Biological Neurons vs Deep Reinforcement Learning: Sample efficiency in a simulated game-world

Forough Habibollahi, Moein Khajehnejad, Amitesh Gaurav, Brett Joseph Kagan
Conference Paper
Neurocomputing
Neuronal Cell Cultures
MaxOne
Neuron
|
2022
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In vitro neurons learn and exhibit sentience when embodied in a simulated game-world

Brett J. Kagan, Andy C. Kitchen, Nhi T. Tran, Forough Habibollahi, Moein Khajehnejad, Bradyn J. Parker, Anjali Bhat, Ben Rollo, Adeel Razi, Karl J. Friston
Journal Article
Neurocomputing
Neuronal Cell Cultures
MaxLab Live
MaxOne
Frontiers in Neuroscience
|
2022
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Long-term morphological and functional dynamics of human stem cell-derived neuronal networks on high-density micro-electrode arrays

Rouhollah Habibey, Johannes Striebel, Felix Schmieder, Jürgen Czarske, Volker Busskamp
Journal Article
Functional Phenotyping
Neuronal Cell Cultures
MaxLab Live
MaxOne
Frontiers in Neuroinformatics
|
2022
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Tracking axon initial segment plasticity using high-density microelectrode arrays: A computational study

Sreedhar S. Kumar, Tobias Gänswein, Alessio Paolo Buccino, Xiaohan Xue, Julian Bartram, Vishalini Emmenegger, Andreas Reinhold Hierlemann
Journal Article
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ACS Sensors
|
2022
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Repeated and On-Demand Intracellular Recordings of Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

Jihyun Lee, Tobias Gänswein, Hasan Ulusan, Vishalini Emmenegger, Ardan M Saguner, Firat Duru, Andreas Hierlemann
Journal Article
Neuronal Cell Cultures
Others
MaxOne
iScience
|
2022
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CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons

Danny McSweeney, Rafael Gabriel, Kang Jin, Zhiping P Pang, Bruce Aronow, ChangHui Pak
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
Journal of Neural Engineering
|
2022
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Inferring monosynaptic connections from paired dendritic spine Ca2+ imaging and large-scale recording of extracellular spiking

Xiaohan Xue, Alessio Paolo Buccino, Sreedhar Saseendran Kumar, Andreas Hierlemann, Julian Bartram
Journal Article
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Molecular and Cellular Neuroscience
|
2022
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Df (h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus

Abdel-Rahman Al-Absi, Sakeerthi Kethees Thambiappa, Ahmad Raza Khan, Simon Glerup, Connie Sanchez, Anne M Landau, Jens R Nyengaard
Journal Article
Disease Modeling
Brain Slices
MaxOne
bioRxiv
|
2022
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A multi-modal fitting approach to construct single-neuron models with patch clamp and high-density microelectrode arrays

Alessio Paolo Buccino, Tanguy Damart, Julian Bartram, Darshan Mandge, Xiaohan Xue, Mickael Zbili, Tobias Gänswein, Aurélien Jaquier, Vishalini Emmenegger, Henry Markram, Andreas Hierlemann, Werner Van Geit
Preprint
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Nature Communications
|
2022
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Functional neuronal circuitry and oscillatory dynamics in human brain organoids

Tal Sharf, Tjitse van der Molen, Stella M. K. Glasauer, Elmer Guzman, Alessio P. Buccino, Gabriel Luna, Zhuowei Cheng, Morgane Audouard, Kamalini G. Ranasinghe, Kiwamu Kudo, Srikantan S. Nagarajan, Kenneth R. Tovar, Linda R. Petzold, Andreas Hierlemann, Paul K. Hansma, Kenneth S. Kosik
Journal Article
Organoids
MaxLab Live
MaxOne
Communications Biology
|
2022
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Suppression without inhibition: how retinal computation contributes to saccadic suppression

Saad Idrees, Matthias-Philipp Baumann, Maria M. Korympidou, Timm Schubert, Alexandra Kling, Katrin Franke, Ziad M. Hafed, Felix Franke, Thomas A. Münch
Journal Article
Functional Phenotyping
Retina
MaxLab Live
MaxOne
Brain Communications
|
2022
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P97/VCP ATPase inhibitors can rescue p97 mutation-linked motor neuron degeneration

F Wang, S Li, T Y Wang, G A Lopez, I Antoshechkin, T F Chou
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxTwo
MRS Bulletin
|
2022
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Functional imaging of brain organoids using high-density microelectrode arrays

Manuel Schröter, Congwei Wang, Marco Terrigno, Philipp Hornauer, Ziqiang Huang, Ravi Jagasia, Andreas Hierlemann
Journal Article
Organoids
MaxLab Live
MaxOne
MaxTwo
Frontiers in Molecular Neuroscience
|
2022
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Aging-dependent altered transcriptional programs underlie activity impairments in human C9orf72-mutant motor neurons

Daniel Sommer, Sandeep Rajkumar, Mira Seidel, Amr Aly, Albert Ludolph, Ritchie Ho, Tobias M Boeckers, Alberto Catanese
Journal Article
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2022
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Automated detection of extracellular action potentials from single neurons

Zhuowei Cheng, Elmer Guzman, Tjitse van der Molen, Tal Sharf, Paul K. Hansma, Kenneth S. Kosik, Linda Petzold, Kenneth R. Tovar
Preprint
Neuronal Cell Cultures
MaxLab Live
MaxOne
Small
|
2022
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A Biodegradable Magnetic Microrobot Based on Gelatin Methacrylate for Precise Delivery of Stem Cells with Mass Production Capability

Seungmin Noh, Sungwoong Jeon, Eunhee Kim, Untaek Oh, Danbi Park, Sun Hwa Park, Sung Won Kim, Salvador Pané, Bradley J. Nelson, Jin-young Kim, Hongsoo Choi
Journal Article
Method Development
Microphysiological Systems
Neuronal Cell Cultures
MaxLab Live
MaxOne
Frontiers in Neuroscience
|
2022
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Recording Saltatory Conduction Along Sensory Axons Using a High-Density Microelectrode Array

Kenta Shimba, Takahiro Asahina, Koji Sakai, Kiyoshi Kotani, Yasuhiko Jimbo
Journal Article
Neuronal Cell Cultures
MaxLab Live
MaxOne
bioRxiv
|
2022
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Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation

Philipp Hornauer, Gustavo Prack, Nadia Anastasi, Silvia Ronchi, Taehoon Kim, Christian Donner, Michele Fiscella, Karsten Borgwardt, Verdon Taylor, Ravi Jagasia, Damian Roqueiro, Andreas Hierlemann, Manuel Schröter
Preprint
Disease Modeling
Neuronal Cell Cultures
MaxLab Live
MaxOne
arXiv
|
2022
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Design strategies for controlling neuron-connected robots using reinforcement learning

Haruto Sawada, Naoki Wake, Kazuhiro Sasabuchi, Jun Takamatsu, Hirokazu Takahashi, Katsushi Ikeuchi
Preprint
Microphysiological Systems
Neurocomputing
Neuronal Cell Cultures
MaxOne
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